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英译中

　　1.Despite the surge of microbial genome data, experimental testing is important to confirm inferences about the cell biology, ecological roles and evolution of microorganisms. As the majority of archaeal and bacterial diversity remains uncultured and poorly characterized, culturing is a priority. The growing interest in and need for efficient cultivation strategies has led to many rapid methodological and technological advances. In this review, we discuss common barriers that can hamper the isolation and culturing of novel microorganisms and review emerging, innovative methods for targeted or high-throughput cultivation. We also highlight recent examples of successful cultivation of novel archae ……此处隐藏5727个字…… e replication or continuous infection of pathogens, enhance the protective immune response to pathogens, reduce the deterioration of inflammation, and maintain the balance of immune response of lesions. Although HDT, including interferon, has been established in the treatment of chronic viral hepatitis, functional drugs aimed at treating persistent viral infection and new strategies for developing broad-spectrum anti-virus against new viruses are still crucial.

　　In chronic bacterial infections (such as tuberculosis), HDT strategies aim to enhance the antibacterial activity of phagocytes, and use soluble molecules (such as anthotetraenoic acid and cytokines) or cytokines (such as costimulatory molecules) to inhibit inflammation.